99% Ectoin In Skincare 96702-03-3

Product Description

UV Repair Assistant raw material Microbial fermentation Purity 99% Ectoine

 

 

Product Details

Product name:	ECTOIN
Description:	Small cyclic amino acid derivatives
CAS NO:	96 702-03-3
Appearance:	white powder
Purity:	≥99%
Recommended addition:	0.2%-2%
Molar mass:	142.16 g/mol
PH:	1-9
Storage conditions:	dry place, at room temperature
Melting point:	280°C
PH(2% solution in water):	6.0~8.0
Boiling point:	381.5°Cat760mmHg
Flash point:	184.5°C
Density:	1.37g/cm3
Usage:	Cosmetic raw material
Grade:	Medicine & Cosmetic

 

 

 

Ectoin is derived from highly halophilic bacteria, an amino acid derivative that exists in microorganisms, and is a cyclic amino acid. It was first discovered in 1985 as a microbial substance that exists in the salt lake of the Natron Valley (Egypt Desert) in Egypt. Under extreme conditions of high salt, high temperature, and high ultraviolet radiation, Ectoin protects halophilic bacteria from harm.

We uses synthetic biology to optimize the fermentation and purification process of Ectoin, which not only improves the purity of Ectoin, but also greatly increases the amount of cell expression.

 

UV Repair Assistant

1.1 Inhibit UVA-induced mitochondrial gene mutations

 

Human fibroblast
1mM tetrahydromethylpyrimidine carboxylic acid pretreated cells for 24h
UVA irradiation (8 J/cm2) cells, 3 times a day, a total of 12 days

Experiments show
UVA can induce the generation of mitochondrial DNA mutation marker "Common Deletion", and 1mM tetrahydromethylpyrimidine carboxylic acid can completely inhibit the generation of UVA-induced mitochondrial DNA mutation

 

1.2 Reduce skin damage caused by UVB

HaCaT-keratinocyte
1mM (0.014%) Ectoin

Ectoin pretreated cells for 24h

UVA irradiation (5 J/cm2) cells

Compared with the UVA-irradiated control group, Ectoin can significantly reduce the damage of UVA to cell DNA.

 

1.3 Tetrahydropyrimidine reduces skin damage caused by UVB

Irreversible damage to cells and the potential risk of mutagenic keratin are the result of direct UVB irradiation

                Histochemical staining of sunburned cells

Our Ectoin reduces skin damage caused by UVB

Histochemical staining detection of HES paraffin sections

Ectoin 0.5% pretreatment for 24h

5 J/cm2 UVB irradiation for 4 days, 3 times a day

 

1.4 Tetrahydropyrimidine reduces melanin production

Ectoin can well protect melanocytes from UVB-induced melanin production, and can form a barrier on the skin surface to resist UVA-induced oxidative stress.

                 Histochemical staining of melanin

 

Histochemical staining detection of FM paraffin sections

Ectoin 0.5% pretreatment for 24h

1.5 J/cm2 of UVB + 22 J/cm2 of UVA irradiation for 4 days, 3 times a day

 

Suggested addition

Anti-allergic, redness 1%-2%

Sun protection, post-sun repair 0.5%-1%

Skin barrier repair 1%

Basic moisturizing (mask) 0.05%-0.1%

Whitening, anti-aging, freckle removal and other functional products are compounded with 0.3%-0.5%

 

 

Our Guarantee on quality

1)Purchasing

Thorough market research, understand the price of raw materials and performance.To the procurement source to understand fully, and fully guarantee the quality of the procurement of raw materials.

2) Inspection

Four steps: sampling, sample pretreatment, measuring and data processing.

3) Producing

a)Each operator must do self-inspection of producs and make the corresponding inspection records.

b)Full-time inspectors through check the operator self-inspection, and review and sign in the corresponding record. Full-time inspection is responsible for inspection of finished product, and make the finished product incoming inspection records.

4) Before selling

Test result can be provided before selling.

Third-party detection institution is allowed if you are not satisfied with test results.

 

Packing: